Peter I Dosa Selected Research

APD791

6/2010

Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): a highly selective 5-hydroxytryptamine2A receptor inverse agonist for the treatment of arterial thrombosis.

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Peter I Dosa Research Topics

Disease

4	Glaucoma 01/2022 - 01/2015
3	Infections 01/2017 - 01/2015
2	Schistosomiasis (Bilharziasis) 12/2019 - 12/2017
2	Obesity 01/2019 - 01/2008
2	Clostridium Infections 01/2017 - 01/2016
2	Sleep Initiation and Maintenance Disorders (Insomnia) 08/2010 - 03/2010
1	Ocular Hypertension (Glaucoma, Suspect) 01/2022
1	Neglected Diseases 12/2019
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2019
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2017
1	Colitis 01/2016
1	Pouchitis 01/2016
1	Stroke (Strokes) 06/2013
1	Acute Kidney Injury (Acute Renal Failure) 06/2013
1	Parkinson Disease (Parkinson's Disease) 02/2013
1	Prolactinoma (Prolactinomas) 02/2013
1	Pituitary ACTH Hypersecretion 02/2013
1	Thrombosis (Thrombus) 06/2010
1	Weight Gain 01/2008

Drug/Important Bio-Agent (IBA)

4	KATP ChannelsIBA 01/2022 - 01/2015
4	Pharmaceutical PreparationsIBA 12/2019 - 01/2015
3	Praziquantel (Biltricide)FDA Link 12/2019 - 01/2015
3	Serotonin (5 Hydroxytryptamine)IBA 08/2010 - 01/2008
2	Cromakalim (Levcromakalim)IBA 01/2022 - 01/2015
2	ProdrugsIBA 01/2022 - 06/2013
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2017 - 01/2016
2	Bile Acids and Salts (Bile Acids)IBA 01/2017 - 06/2013
2	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 08/2010 - 06/2010
1	SteroidsIBA 01/2022
1	Diazoxide (Hyperstat)FDA Link 01/2022
1	Ophthalmic Solutions (Eye Drops)IBA 01/2022
1	AnthelminticsIBA 12/2019
1	Taurocholic Acid (Sodium Taurocholate)IBA 01/2017
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 01/2017
1	Retinaldehyde (Retinal)IBA 01/2017
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 01/2017
1	GalaninIBA 01/2017
1	Adenosine Triphosphate (ATP)IBA 01/2016
1	PotassiumIBA 01/2016
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2016
1	Latanoprost (Xalatan)FDA Link 01/2015
1	Cabergoline FDA LinkGeneric 02/2013
1	Dopamine Agonists (Dopamine Agonist)IBA 02/2013
1	AmidesIBA 08/2010
1	APD791IBA 06/2010
1	Urea (Carbamide)FDA LinkGeneric 03/2010
1	nelotanserinIBA 03/2010
1	5-HT2C Serotonin ReceptorIBA 01/2008
1	lorcaserinIBA 01/2008

Therapy/Procedure

7	Therapeutics 01/2019 - 01/2015
1	Fecal Microbiota Transplantation 01/2016
1	Intravenous Administration 06/2013